The main causes of abdominal burning sensation are as follows: 1. Excessive secretion of gastric acid: mainly due to dietary factors, drug factors, and gastric mucosal lesions leading to increased secretion of gastric acid, the increased gastric acid stimulates the gastric mucosa, esophageal mucosa, and duodenal mucosa, which can lead to heartburn, acid reflux, and abdominal burning sensation. 2. Damage to the gastrointestinal tract mucosa: mainly due to inflammation, physical damage, chemical damage, and stress reaction. 3. Gastrointestinal perforation: Especially gastric perforation, after gastric perforation, a large amount of gastric acid and acidic contents flow into the abdominal cavity, resulting in the corrosion of abdominal tissues and organs by gastric acid, resulting in burning pain in the whole abdomen, accompanied by fever, nausea and other symptoms, The pain is accompanied by fever, nausea and other symptoms, and a positive peritoneal irritation sign is seen on physical examination.