Urticaria is an allergic skin disease with a very complex pathogenesis and prone to recurrent attacks. Therefore, oral medications alone are not very effective and are more common in clinical practice. You can change the oral medication or carry out other therapies, for example, if the patient’s oral antihistamine medication is not effective, you can combine other antihistamine medications together, one is not good, two is not good, you can use a variety of combination, or even combine with immunity-boosting therapies, such as using histamine human immunoglobulin to do acupuncture point injection therapy in Chinese medicine, Quchi, Blood Sea, Sanyinjiao and other points to inject, the effect is also good. In addition, there are also some self-blood therapy, tissue therapy, including acupuncture therapy in Chinese medicine, ear acupuncture, etc., the effect is good. Patients are advised to find the trigger for the onset of urticaria, which is the allergen, and only by avoiding contact with the allergen will they be able to better control the onset of urticaria.