Quadrivalent vaccine generally refers to quadrivalent cervical cancer vaccine. After receiving this vaccine, patients should pay attention to dietary care, observation of the vaccination site, wound care and so on. 1. Dietary care: after vaccination, patients should pay attention to light diet, eat more easy-to-digest and nutritious food, such as egg custard, milk, chicken, vegetables, fruits, etc., and avoid spicy and stimulating food. 2. Observe the reaction after vaccination: some patients may have red, swollen and hardened skin, and a few will have fever, nausea, vomiting, fatigue, rash and other systemic symptoms. Temperature should be measured, and the adverse reactions should be observed. The above symptoms can subside naturally in 2-3 days, but if there is any abnormality, medical treatment should be sought in time. 3. Wound care: avoid bathing within 24 hours after vaccination, so as to avoid bacterial infection secondary to the contact of the vaccinated part of the needle eye with the bathing water. Quadrivalent cervical cancer vaccine only plays a preventive role and cannot avoid the disease completely. It is recommended that women have regular gynecological examination and avoid unclean sex.