Mitral valve replacement is categorized into mechanical and biological valves. Mechanical valves cost around 50,000-100,000 yuan for one valve and 100,000-150,000 yuan for two valves, while biological valves cost around 100,000 yuan for one valve and more than 150,000 yuan for two valves. The difference between biologic and mechanical valves is that mechanical valves work for a longer period of time, but require lifelong anticoagulant medication. Biologic valves have a shorter lifespan and need to be replaced periodically, but they do not require anticoagulant medication, and the longest duration of a biologic valve can last up to 20 years. Once the valve replacement surgery, the postoperative need to strictly control the infection, whether it is the respiratory system, digestive system or urinary system infection, once the bacteria into the bloodstream, it is easy to form endocarditis, affecting the activity of the prosthetic valve, after the infection must be timely medical treatment, early application of antimicrobial control. It is also necessary to control the emergence of heart failure and arrhythmia, and apply cardiotonic agents and diuretics if necessary.