Pentavalent rotavirus and pentavalent rotavirus are different vaccines that mainly prevent different types of diseases. Pentavalent rotavirus vaccine can prevent five serotypes of rotavirus, including serotypes G1, G2, G3 and other subtypes of rotavirus through one vaccination. However, the pentavalent rotavirus vaccine only protects against rotavirus and does not protect against other pathogens. Pentavalent vaccine is a vaccine that includes five kinds of antigenic substances, such as DPT, inactivated polio vaccine, Hib vaccine, tetanus vaccine, diphtheria vaccine, etc. Pentavalent vaccine is a combination of five different kinds of vaccines, which has preventive effect on five kinds of pathogens, so it is more effective. Vaccination needs to be carried out in a professional vaccination site to avoid adverse reactions.