High LDL is the presence of elevated LDL cholesterol. For elevated LDL cholesterol, patients are recommended to prefer statin lipid-lowering drugs, such as simvastatin, atorvastatin, and rasulvastatin. Relatively speaking, these drugs can not only lower LDL cholesterol, but also help to lower total cholesterol and raise HDL cholesterol. However, while taking these drugs, it is important to monitor liver function, kidney function and cardiac enzymes, and patients are advised to pay attention to the presence of lower limb pain and other uncomfortable symptoms. If LDL cholesterol cannot be lowered to the standard range by taking statins alone, it can be combined with ezetimibe, which is a cholesterol absorption inhibitor and can lower LDL cholesterol relatively better. If a patient cannot take either ezetimibe or a statin, he or she may choose to take oral lipocalin to lower LDL cholesterol.