Daily work, medical, pharmaceutical, nursing and other medical workers, the dosage form of drugs, dose, dosage usage, quantity, etc. are very concerned about, but another factor affecting the efficacy of drugs is rarely observed, that is, the drug is protected from light. Some of the old need to avoid the light of the drug, at present can relatively take a better protection from light. But nowadays, with the continuous development and progress of the pharmaceutical industry, the variety of drugs has increased greatly. And our grassroots practitioners, the relative lag of relevant knowledge and related academic expansion is not timely, thus leading to the current situation. If the drugs that need to be protected from light do not take appropriate measures, not only will their efficacy be reduced, and even poisoning, such as sodium nitroprusside, its aqueous solution is unstable, the decomposition of light accelerates, will first decompose into potassium ferricyanide hydrate and nitrogen oxide, and potassium ferricyanide hydrate will then decompose into highly toxic hydrocyanic acid, and Prussian blue. First of all, to understand, those drugs need to avoid light: 1, prone to photochemical degradation of drugs. 1.1, sodium nitroprusside 1.2, pyridine drugs Nifedipine, nimodipine, cilnidipine, nifedipine and other structures containing light unstable structures. In storage and infusion should be protected from light. 1.3.Vitamins Water-soluble vitamins, vitamin B6, vitamin C, etc. 1.4, thiazides Promethazine hydrochloride, chlorpromazine hydrochloride 1.5, quinolones Ciprofloxacin, levofloxacin, lomefloxacin, fleroxacin, etc. 1.6, others Hydrocortisone, prednisone, furosemide, reserpine, procaine, etc. 2, easily oxidized drugs Generally, the structure of such drugs contain more easily oxidized group. Such as phenols, aromatic amines, pyrazolones, thiazides. These drugs are extremely easy to be oxidized, and light is a big accelerating factor of oxidation reaction, so the above drugs should be protected from light. 2.1 Phenolic drugs Epinephrine, norepinephrine, norepinephrine, dopamine, morphine, etc. 2.2 Aromatic amine drugs Sodium p-aminosalicylate. 2.3 Drugs containing unsaturated carbon bonds. Amphotericin B 3. Antitumor drugs Carboplatin, cisplatin, oxaliplatin, cyclophosphamide, fluorouracil, mitomycin, epirubicin, vincristine, dacarbazine, etc. 4. Other common drugs Lipoic acid, methylcobalamin, calcium folinate, naloxone, guipizide maleate, omeprazole sodium, etc. Secondly, we have to do the corresponding improvement for the current work. Now there are corresponding light-proof infusion supplies, but they are not only expensive, and the safety is still uncertain. This requires our pharmaceutical workers to open their minds to think of ways to do some simple light-absorbing appliances by themselves. At the same time, in the usual work, strengthen the safety awareness of medication, starting from themselves, from the medical ethics, pharmacological ethics, nursing ethics, so that patients can use medication more safely and effectively. Finally, I hope that the relevant departments can increase the publicity of new knowledge of medicine, and also put forward an initiative to all colleagues to strictly require themselves at work and strengthen their study in general.