Rheumatoid arthritis patients with fever for two months may be due to rheumatoid arthritis disease itself, may also be microbial infections, malignant tumors and other causes, need to further clarify the cause of the disease to take medication or other ways of treatment. 1. Rheumatoid arthritis: rheumatoid arthritis disease may appear in the early weeks of fever, mostly low-grade fever, rheumatoid arthritis can be used for ibuprofen, aspirin and other non-steroidal anti-inflammatory drugs, or adalimumab, salicylsulphonyl pyridine and other anti-rheumatic drugs and other drugs for treatment, and at the same time, bed rest, to ensure that sufficient rest time. 2. Microbial infections: bacteria, mycoplasma, viruses and other microorganisms can also lead to persistent fever symptoms, can be clear through the laboratory auxiliary examination of the pathogens using targeted antibiotic therapy, such as ceftazidime, ampicillin, etc., the cause of the disease can be clearly defined, but also depending on the patient’s condition, the use of non-steroidal anti-inflammatory drugs to reduce fever treatment. 3. Malignant tumors: a variety of malignant tumors may lead to persistent fever symptoms, the need to clarify the cause of the specific malignant species type of anti-tumor drugs such as erythromycin, methotrexate, etc., or ibuprofen, aspirin and other antipyretic and analgesic treatment, and other treatments. Rheumatoid arthritis patients with fever for two months may have other reasons, it is recommended that patients to the regular hospital rheumatology and immunology department and other related departments to further clarify the diagnosis, and follow the doctor’s instructions for treatment.