Taking tuberculosis medication with high bilirubin triple is usually caused by liver side effects due to medication, and it is recommended that the patient should seek medical advice in time and change medication or receive timely treatment under the guidance of the doctor. Bilirubin three generally refers to total bilirubin, conjugated bilirubin and unconjugated bilirubin, and is commonly used in clinical practice to check whether there is any disease in the liver. Long-term use of anti-tuberculosis drugs can have an impact on the liver. If bilirubin is elevated but aminotransferase is normal, it indicates that the liver is only slightly damaged, and liver-protecting drugs can be taken under the guidance of the doctor, and common liver-protecting drugs include glycyrrhizic acid glycosides, silymarin, and so on. Taking tuberculosis drugs with high bilirubin is usually due to liver side effects caused by drugs, it is recommended that patients take additional tests to determine the cause, and receive timely treatment under the guidance of a doctor.