High urine specific gravity in urine routine may be caused by physiological reasons such as drinking too little water or sweating too much, or it may be caused by pathological reasons such as glomerulonephritis, nephrotic syndrome, diabetic nephropathy and other diseases. 1. Physiological reasons: under normal circumstances, patients may have high urine specific gravity due to the concentration of urine caused by drinking too little water or sweating too much. 2. Pathological causes: If there is an increase of protein in the urine, such as various nephritis, nephrotic syndrome, diabetic nephropathy and other diseases, it may cause an increase of urine specific gravity. In addition, in the case of heart failure, high fever, shock and other conditions that lead to the concentration of urine, may also cause an increase in the specific gravity of urine. If patients find high urine specific gravity in urine routine, it is recommended to go to regular hospitals in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or treatment under the guidance of the doctor.