Spiny bumps on the sides of the vagina may be caused by warts, vaginal inflammation and other causes. 1. Condyloma acuminatum: a lesion of warty proliferation of squamous epithelium caused by HPV (human papillomavirus) infection. It can be manifested as scattered or clustered proliferation of pink or white small papillary warts, lesions can be fused after the enlargement of the crown or cauliflower-like, inspection can be seen in the vagina warty bumps, through the typical appearance, pathological examination can be initially diagnosed. 2. Vaginal inflammation: caused by inflammation stimulation of the vaginal mucosa, can also be accompanied by increased vaginal discharge, vulvovaginal itching and other symptoms, can be combined with the clinical manifestations and vaginal secretion examination to clarify the diagnosis. When there are prickly bumps on both sides of the vagina in the clinic, you can go to the hospital in order to find out the cause and then actively deal with it.