Patients with high hepatitis B viral index need to meet certain criteria before they are suitable to have children. Those with abnormal liver function should be treated with antiviral therapy until their liver function is normal before they can prepare for pregnancy, and the viral load needs to be rechecked regularly during pregnancy, and antiviral therapy should be continued if necessary, and the babies need to be blocked after birth. 1. Elevated aminotransferases: If the aminotransferases are elevated, it is recommended to receive antiviral treatment, such as tenofovir and entecavir, etc., and wait until the liver function is normal before considering pregnancy. 2. No elevated transaminases: In this case, you can prepare for pregnancy directly. In both cases, the viral load should be checked regularly during pregnancy, and if the viral load during pregnancy is greater than 10^5IU/ml, the pregnant woman should take tenofovir blockade from 26 weeks, and the newborn needs to be vaccinated with hepatitis B vaccine and hepatitis B immunoglobulin after birth. Hepatitis B virus has a greater danger, can be transmitted through mother-to-child transmission, so patients with hepatitis B preparation, pregnancy and breastfeeding should be under the guidance of a physician to prevent and control work, to reduce the chances of infants being infected, do not be negligent, so as not to cause serious consequences.