The causes of pressure pain at the lower edge of the right rib cage are as follows: First, it is mainly due to inflammation of the rib cartilage or intercostal neuralgia. This is usually due to a local inflammatory reaction after strenuous exercise or exertion, mainly manifested as stabbing pain and soreness, which can also radiate along the rib cage to the chest and back when the pain is severe. It is usually treated with medication, such as topical application of Fotarine or oral administration of non-steroidal anti-inflammatory and analgesic drugs. If the pain point is fixed and the pain level is severe, local closure treatment can also be performed. Secondly, cholecystitis or liver disease may also cause pressure pain or hidden pain at the lower edge of the right rib cage, which requires an ultrasound examination of the abdomen for a clear diagnosis. If it is confirmed to be cholecystitis, medication is needed; if it is other diseases of the liver or injurious lesions, further treatment by a specialist is needed.