The need for puncture of cerebral white matter demyelination needs to be analyzed comprehensively; ischemic cerebrovascular disease does not need it, while inflammatory demyelinating diseases often require puncture.
Cerebral white matter demyelination caused by ischemic cerebrovascular disease is mostly located in bilateral lateral ventricles, patients often have no obvious clinical symptoms, some patients may have dizziness, mild limb weakness and cognitive decline and other symptoms, the case of cerebrovascular disease for the second level of preventive treatment can be used, commonly used medications such as aspirin, atorvastatin, etc., and pay attention to the control of cerebrovascular disease risk factors, do not need to be done puncture.
Inflammatory diseases such as multiple sclerosis and optic neuromyelitis optica that cause demyelination of the brain white matter, patients often experience recurrent blurred vision, diplopia, unilateral numbness and weakness of the limbs, etc. Multiple or long segmental demyelination changes are also commonly seen in cranial nuclear magnetic resonance imaging (NMRI) and spinal nuclear magnetic resonance imaging (NMRI). In such cases, lumbar puncture is often necessary to obtain cerebrospinal fluid for relevant immunologic tests.
In the case of cerebral white matter demyelination, it is recommended to seek prompt medical attention, follow the doctor’s instructions for relevant examinations, and actively carry out treatment to avoid delaying the condition.