Four Substances Soup and Gui Spleen Pill can be taken together, but the medication should be taken according to the doctor’s instructions. Four Substances Soup and Rejuvenating Spleen Pill both have some of the same effects, and both can be taken together to enhance their effects. Four Substances Soup consists of Angelica sinensis, Rhizoma Ligustici Chuanxiong, Radix Paeoniae Alba and Radix Rehmanniae Praeparata, which can nourish and regulate Blood. It is used for Chong Ren deficiency (damage to the Chong and Ren veins, affecting women’s menstruation and fertility). Irregular menstrual flow, pain in the umbilicus and abdomen, and leakage in collapse. Hard mass in the blood impediment with occasional pain. Restlessness of the fetus during pregnancy, incessant discharge of blood, and post-partum malignant discharge, lumps in the abdomen, firmness and pain in the lesser abdomen, with chills and fever at times. Gui Spleen Pill is composed of Radix Codonopsis Pilosulae, Rhizoma Atractylodis Macrocephalae and Radix Astragali Praeparatae, etc. It can benefit the qi and strengthen the spleen (to regulate the qi of the spleen and stomach), nourish the blood and calm the spirit (to stabilize the spirit and soothe the emotions by nourishing the blood). It is used for heart and spleen deficiency (weakness of the heart and spleen), shortness of breath and palpitation (rapid heartbeat, often accompanied by panic), insomnia and dreaminess, dizziness, tiredness and weakness of limbs, and loss of appetite. Gastrointestinal discomfort, skin rash and other discomforts may occur after taking it. Patients are advised to take the medicine under the guidance of a doctor.