The amount of fluid to be pumped for the first time in a pericardial effusion should not exceed 100 ml. There are special reasons for the amount regulation, and it is not better to pump as much as possible. Under normal circumstances, the pericardial cavity shows a slightly negative pressure. In the event of a pericardial effusion, if a large amount of fluid is rapidly pumped out, the pressure in the pericardium will rapidly decrease, which will have an impact on the pumping function of the heart, leading to an impact on the filling and contraction of the chambers of the heart, and may even induce heart failure. When performing the first aspiration of pericardial effusion, not only should too much fluid be withdrawn, but also care should be taken that the speed should not be too fast when performing the puncture. The purpose of performing pericardial puncture aspiration is to relieve pericardial compression, maintain the basic physiological activities of the heart and ensure blood supply to the body. The clinical symptoms will be effectively relieved after the pericardial puncture and fluid extraction is performed. After the puncture and fluid extraction, the symptoms of cardiac compression should be further observed and whether they can be relieved soon.