Patients with dry syndrome who have been taking medication but still aggravated may be that the medication has not been effective, or the treatment program is not effective enough to control the disease, etc. It is recommended to consult a doctor in a timely manner, and increase the dosage of the medication or adjust the treatment program after the doctor has evaluated the case. Dry syndrome mainly involves the patient’s exocrine glands, resulting in symptoms such as dry mouth, dry eyes, swollen and painful parotid glands, and it can also involve multiple organ systems throughout the body. If the patient’s condition worsens despite taking medication, it may be because the medication has not worked, or the treatment program has not been effective enough to control the condition, etc. It is recommended to consult a doctor in a timely manner. After the doctor’s evaluation, increase the dosage of medication, such as non-steroidal anti-inflammatory drugs (NSAIDs) such as celecoxib, antimalarials such as hydroxychloroquine, glucocorticosteroids such as prednisone acetate, and immunosuppressants such as methotrexate, etc., or adjust the original treatment plan and replace it with a new treatment plan. It is recommended that patients with a confirmed diagnosis of dry syndrome go to the rheumatology and immunology departments of regular hospitals for related consultations.