Aspirin has antipyretic and analgesic, anti-inflammatory and anti-rheumatic, anti-thrombotic and other effects, taking may appear nausea, vomiting, epigastric discomfort or pain, gastric bleeding, skin rashes, liver and kidney function impairment and other side effects. Aspirin is commonly used in clinical practice for rheumatic fever, arthritis, Kawasaki disease, myocardial infarction, atrial fibrillation and other diseases, with antipyretic and analgesic, anti-inflammatory and anti-rheumatic, anti-thrombotic and other effects. Side effects such as nausea, vomiting, epigastric discomfort or pain, gastric bleeding, skin rash, liver and kidney function impairment may occur when taking aspirin. For surgical patients, aspirin should be discontinued 5 days before surgery; aspirin should not be used after drinking alcohol; it should not be used by ulcer patients or people with blood clotting disorders. Aspirin is contraindicated in people who are allergic to aspirin components, in ulcer disease or other active bleeding with bleeding symptoms, in hemophilia or thrombocytopenia, and in people with glucose 6 phosphate dehydrogenase deficiency. Aspirin should be used in strict accordance with medical advice, and if any of the above discomforts occur, immediate medical attention should be sought.