Does elevated transaminases indicate liver problems?

Elevated aminotransferases do not necessarily mean that there is a problem with the liver. Aminotransferases include glutathione and glutamic oxalacetic aminotransferases, especially glutamic oxalacetic aminotransferases, which are mainly found in the heart muscle, skeletal muscle, liver, kidney, etc., especially the heart muscle has a higher content. Most of the elevated glutathione is seen in damaged myocardium, such as myocarditis, myocardial infarction, heart failure, and various cardiomyopathies. Glutathione is also seen in skeletal muscle damaging diseases, such as rhabdomyolysis syndrome, progressive muscular dystrophy, and dermatomyositis after strenuous exercise, which can also lead to an increase in glutathione transaminase. In cases of impaired renal function, such as renal failure, chronic glomerulonephritis, and nephrotic syndrome, elevated glutathione aminotransferase may also be the main manifestation.