The clinical side effects of Eusemide are as follows: First, gastrointestinal reactions such as nausea, vomiting and anorexia can occur, which usually do not require treatment, and most of them can disappear on their own with continuous dosing. Second, irregular vaginal bleeding can occur, often due to irregular vaginal bleeding caused by missed doses of the drug. Therefore, when taking Eusemide, it is recommended to take it orally at a fixed time so that it will not be missed. Third, amenorrhea can occur. If a patient with irregular menstruation takes the drug, amenorrhea may occur afterwards. Fourth, it must be taken every day. Once taken and missed, it can cause irregular vaginal bleeding.