There are more hormones involved in blood glucose regulation, mainly including insulin and glucagon. In addition, glucocorticoid, thyroid hormone and growth hormone can also be involved in raising blood sugar when the body is under stress and growth. Therefore, the regulation of blood glucose in the body is the result of the combined action of many hormones.1. Insulin: Insulin is the first hormone involved in blood glucose regulation and the only hormone that can lower blood glucose concentration, which is secreted by pancreatic beta cells. By combining with insulin receptors, insulin can open the channels on the cells, so that glucose in the plasma can enter the cells, which can help the body lower blood sugar, and at the same time can generate energy, and can promote the synthesis of protein and fat; 2, glucagon: there are more hormones that raise blood sugar, and pancreatic alpha cells can secrete glucagon, which can antagonize the role of insulin and have the effect of raising blood sugar. Glucocorticoids: mainly secreted by the adrenal glands, glucocorticoids secreted by the adrenal cortex belong to the stress hormones of human body and have obvious effects on raising blood sugar; 4. thyroid hormones: excessive secretion of thyroid hormones will lead to an increase in blood sugar level, because thyroid hormones are also a type of hormones that antagonize insulin and have the effect of raising blood sugar. Therefore, patients with hyperthyroidism can observe a significant increase in blood glucose level after meals. 5. Growth hormone: It also has the effect of antagonizing insulin, which can increase blood glucose level, and when growth hormone is secreted inappropriately, it will lead to a larger increase in blood glucose, resulting in several times higher blood glucose level. 6. Other hormones: such as sex hormones, although they do not play an obvious role in blood sugar regulation, some people may experience blood sugar fluctuations when sex hormones fluctuate, for example, type 1 diabetic patients may experience an increase in blood sugar level when they have their menstrual cycle.