1, tobacco dependence is a chronic disease tobacco dependence is a chronic and highly recurrent disease, only a few smokers quit completely the first time, most smokers need several attempts to finally quit. 2, to promote the harm of smoking and the benefits of quitting Quit smoking before the age of 30 can reduce the risk of lung cancer by 90%; quit smoking 5 years after the risk of oral and esophageal tumors caused by smoking is reduced by half; quit smoking after the risk of heart disease is reduced more rapidly, within 1 year of smoking caused by death will be reduced by half, 15 years of absolute risk and never smokers similar; quit smoking can mildly increase lung function, reversing the rate of lung function reduction. 3. 5A method for those who are willing to quit Ask (ask). Ask smokers about their basic conditions, and implement a system of questioning, preferably using a uniform record-keeping system. Advice. Reinforce the smoker’s awareness of the need to quit, and use a clear, strong, personalized approach to urge smokers to quit, so that they are aware of the dangers of smoking and get out of their misconceptions. Assess. Identify the smoker’s willingness to quit. Assist. This includes helping the smoker to develop the right attitude, reviewing the reasons for quitting, setting a quit date, signing a quit agreement, choosing an appropriate quit method, using quit medication, managing withdrawal symptoms, reminding the persistent quitter to prevent relapse, and providing cessation science materials and telephone counseling. Follow-up visits (arrange) Long-term follow-up visits should be arranged after the smoker has started to quit, preferably for 6 months. 4. Appropriate cessation methods for physical dependence (physical dependence): smoking cessation medication. Treatment of psychological dependence: psychological support. The best program for treating tobacco dependence: a combination of medication and behavioral therapy.