The chances of a gastric ulcer biopsy being malignant are not great. Pathologic biopsy of gastric ulcer patients can be used to diagnose the benign and malignant nature of gastric ulcers. In general, most gastric ulcer biopsy results are benign, and after acid suppression treatment such as omeprazole and lansoprazole, symptoms such as gastric pain, nausea, vomiting, acid reflux, heartburn and other symptoms can be relieved, and healing of the ulcer surface can be promoted. Gastric ulcers combined with Helicobacter pylori infection need to be treated with a combination of two antibiotics and bismuth in addition to acid suppressants. Gastric ulcer patients undergo biopsy, and a small percentage of the test results show malignancy. In addition to basic gastric ulcer manifestations such as postprandial stomach pain and burning sensation in the stomach, patients may be accompanied by symptoms and signs such as weight loss, fever, anemia, blood in stools, vomiting of blood, and an epigastric mass. Patients with gastric ulcers should seek prompt medical attention for a definitive diagnosis and targeted treatment. In addition, the above drugs should be taken under the guidance of a doctor and should not be used without authorization.