Blisters on the hands may be caused by herpes sweat, ringworm or contact dermatitis, it is recommended that the patient under the guidance of a doctor to clarify the specific cause of the disease, through oral medication with topical medication to carry out treatment. 1. Sweat herpes: Sweat herpes belongs to a kind of sweat not good eczema. The blisters can be used externally with glycerine lotion, and when the itching is severe, antihistamines such as loratadine and levocetirizine hydrochloride can be taken orally. 2. ringworm: hand long blisters can also be seen in the blister type ringworm, in the treatment can be used externally antifungal drugs, such as ketoconazole lotion, terbinafine cream. If the effect of external drugs is not good, or the lesion area is large, you can take oral antifungal drugs such as itraconazole, terbinafine. 3. Contact dermatitis: contact dermatitis is related to contact with certain irritating or sensitizing substances, and can be treated with topical glycerite lotion. In severe cases, topical glucocorticoid drugs, such as hydrocortisone butyrate cream, dianabed cream and so on, can be used. Combined oral antihistamines such as ebastine are also used. In addition, re-exposure to disease-causing factors needs to be avoided. For patients with blisters on their hands, it is recommended to go to a regular hospital for timely examination and standardized treatment under the guidance of a professional doctor. Drugs need to be used in accordance with medical advice.