Cutting chili peppers by hand and feeling the skin hot and spicy is due to the process of cutting chili peppers, chili peppers contain capsaicin and other substances, contact with the skin may cause the appearance of skin hot and spicy feeling. Generally, you can consider rinsing with cool water, and in the case of more serious symptoms, you can use topical medication (hydrocortisone cream) to eliminate them. 1. Cool water rinsing: Generally, the concentration of capsaicin and other substances on the skin can be washed away by localized cool water rinsing. Since capsaicin is alkaline and soluble in acetic acid and alcohol, the affected area can be scrubbed with white wine or vinegar and then rinsed with water. 2. Local medication: If the symptoms are not relieved after washing with water, and the local skin is red, swollen, painful and other symptoms, you need to consult a doctor in time, and follow the doctor’s instructions to use hydrocortisone cream, tretinoin cream and other glucocorticosteroid medications, to eliminate the hot and spicy sensation. Under normal circumstances, in the process of cutting chili peppers, the hands appear hot and spicy feeling is a normal phenomenon, generally can be relieved by themselves. If the symptoms are more serious and have not been effectively relieved, you need to consult a doctor for treatment.