Statin-induced elevation of bilirubin can usually be gradually recovered after a month of drug withdrawal. Statins mainly act as a lipid-lowering agent, preventing atherosclerosis and restenosis of the blood vessels in the heart. However, they may cause some damage to the liver, with side effects such as increased aminotransferases and increased bilirubin. Elevated bilirubin, usually caused by statin use, is relatively straightforward and effective in terms of treatment recovery. If it is not possible to stop the use of medication, you can follow the doctor’s instructions to choose to replace such as inosine tablets, adenosine triphosphate and other less toxic side effects of similar therapeutic effect of drugs, so that the bilirubin will also gradually return to normal. When bilirubin is elevated while taking statins, it is recommended that you talk to your primary care physician as soon as possible and change your medication accordingly. The medication should be used under the supervision of a doctor.