A lump of flesh in the innermost part of the gums is painful and swollen may be caused by gum polyps, wisdom tooth pericoronitis, periodontal abscess, etc., which can be treated under the guidance of the doctor through general treatment, medication (ibuprofen, metronidazole, etc.), surgery and other methods. 1. Gingival polyps: a pile of flesh inside the gums is painful and swollen may be caused by gum polyps, due to dental caries, food impaction and other factors, long-term stimulation of the gums, hyperplastic polyps, the need for surgical removal of gingival polyps, timely treatment of dental caries, removal of decayed tissues after filling, repair. 2. Wisdom tooth pericoronitis: If it occurs in the site located around the wisdom teeth, it will cause wisdom tooth pericoronitis, and the wisdom tooth eruption is incomplete to form a blind pocket, you can maintain oral hygiene, gargle with a mouthwash, avoid spicy and irritating food, but also under the guidance of the doctor, take ibuprofen, minocycline, aspirin and other drugs for treatment. 3. Periodontal abscess: Due to the damage to the gums and bacterial infection, it can lead to pain and swelling of the innermost piece of flesh of the gums, which can be treated with metronidazole, ornidazole and other medications under the guidance of a doctor and with local periodontal treatment. It is recommended that patients go to the hospital in a timely manner, under the diagnosis of the doctor, according to the patient’s specific condition, to take targeted treatment, life to maintain oral hygiene.