Ectopic pregnancy killing injection, namely methotrexate, is mainly indicated for patients with unruptured ectopic pregnancy and no active intra-abdominal bleeding. Patients with good general condition, no fetal heartbeat on transvaginal ultrasound, mass diameter ≤4cm, and serum hcg less than 5000mIU/mL have a higher chance of success through conservative treatment at this time. However, during this period, attention should be paid to the individual’s specific situation. During the treatment with medication, attention should be paid to the blood test of HCG value, to make sure that there is no increase in HCG value, and there is no severe stomach pain or obvious bleeding, conservative treatment can be taken. If these conditions are not met, it is best to treat the symptoms as soon as possible and in a timely manner to avoid life-threatening effects.