Cirrhosis splenomegaly cannot be restored to normal by spleen removal, the removed spleen cannot regenerate naturally, and is prone to post-resection adverse effects such as thrombosis of the portal vein system. Splenomegaly occurs in cirrhotic patients because after cirrhosis of the liver, the blood vessels in the liver are compressed and the pressure increases, resulting in poor blood flow back to the hepatic blood vessels, which leads to the gradual formation of splenic stasis, splenic fibroplasia and enlargement of the spleen. Spleen enlargement is usually followed by hypersplenism, which phagocytosis of excessive blood cells, causing a decrease in white blood cells and platelets, etc. Therefore, removing the spleen can help to restore the blood cell level. The spleen is a non-renewable organ, and after removal, the missing spleen cannot grow back, meaning that it cannot return to normal, and after splenectomy, post-splenectomy adverse effects such as thrombosis of the portal vein system, pancreatic fistula and localized fluid retention, and abdominal infections may also occur.