There is no fastest clinical solution for high jaundice index in infants. Physiological jaundice needs no treatment, while pathological jaundice can be treated with phototherapy, medication and blood exchange.
1. Physiological jaundice: physiological jaundice mostly appears in 2~4 days after birth, and in full-term babies, it usually subsides within 2 weeks, while in premature babies, it may be delayed to 3~4 weeks. Usually, physiologic jaundice does not need special treatment and can subside naturally, so mothers can strengthen infant feeding.
2. Pathological jaundice: Jaundice mostly appears within 24 hours after birth, the duration of jaundice is more than 2 weeks in full-term infants and more than 4 weeks in preterm infants, and it can reappear after the jaundice subsides. For infants diagnosed with pathological jaundice, phototherapy such as blue light irradiation can be used to promote the excretion of unconjugated bilirubin, and some of the infants can be treated with immunoglobulin infusion and albumin supplementation as prescribed by the doctor.
Some children with pathologic jaundice can be treated with phenobarbital, which induces hepatic enzyme activity and promotes hepatic metabolism of unconjugated bilirubin. In more severe cases, blood transfusion therapy may be performed if necessary. The prognosis is usually good with minimal sequelae in those who are treated aggressively.
Infants with high jaundice index are advised to undergo further investigations to determine the type of jaundice and to follow the treatment prescribed by the doctor, as well as regular medical follow-up. The above medications should be used in accordance with medical advice.