According to the specific situation, you can take the use of tweezers to clip out, medical instruments to remove, surgical removal and other ways to get out. 1. Use tweezers to clip out: if you can see the obvious end of the thorn in your hand, you can use tweezers to clip it out and apply iodine povidone to the wound area in time to avoid wound infection. 2. Removal with medical instruments: If the thorn in your hand cannot be observed with the naked eye, you can use a microscope to find the specific location of the thorn with the help of a doctor, and then the doctor will remove the thorn with sterilized medical instruments. 3. Surgery: If the splinter in your hand is in a deeper location, especially near blood vessels or nerves, it usually needs to be removed by dilatation surgery or debridement surgery. If you have a splinter in your hand, you need to go to the hospital in time to take the correct removal method, and pay attention to the wound care to reduce the possibility of infection.