The second joint pain of the toe may have the following reasons: First, gout, gout most often involves the joints is the joints of the toes, then there can be pain in the joints of the toes, accompanied by redness and swelling, as well as an increase in skin temperature, the serious will have gout stone formation, this time to carry out a blood uric acid test for early diagnosis, diagnosis after the lowering of uric acid medication; Second, rheumatoid, when there is Rheumatoid, when there is rheumatoid rheumatoid can also involve the joints of the toes, then there can be pain and swelling of the joints, and in severe cases, there will be deformity; third, toe neuritis or toe neuroma, toe neuritis or toe neuroma patients can also appear in the second joint of the toes, and then we should carry out the relevant physical examination for diagnosis; fourth, tumors, if there are tumors of the toes, there can also appear in the second joint of the toes, then we should carry out relevant X-ray, foot X-ray, and other relevant examinations to diagnose. Fourth, tumor, if there is a tumor in the toe, the pain in the second joint of the toe can also occur, then we should carry out the relevant X-ray film and nuclear magnetic examination to carry out early diagnosis and treatment.