Myeloma is known as multiple myeloma, and its characteristics include persistent progressive aggravating bone pain, progressive anemia, recurrent infections, electrolyte disorders, and neurological damage. Myeloma is a kind of malignant tumor of hematological system, preferred in middle-aged and old people aged 40-60, with bone pain as the main symptom in clinic, and the treatment is mainly based on radiotherapy, supplemented by surgery, with poor prognosis. 1. Bone pain: persistent, progressive, aggravating bone pain, preferably in lumbosacral region, thorax and limbs. 2. Progressive anemia: myeloma leads to anemia caused by hematopoietic dysfunction, which is mostly manifested as emaciation and general weakness. 3. recurrent infection: common in respiratory system and urinary system, often combined with viral infection. 4. Electrolyte disorders: such as hypercalcemia. 5. Nervous system damage: peripheral neuropathy, nerve root syndrome and so on. The characteristics of multiple myeloma also include renal damage, serum globulin increase and so on. If patients have the above symptoms, they should seek medical treatment in time and receive regular treatment under the guidance of physicians to avoid delaying the condition.