Rhinitis, nose picking and other causes of small-scale nasal mucosal erosion is generally not serious, if the mucosal erosion caused by malignant tumors or special diseases, should be taken seriously. Slight, small-scale erosion of the nasal mucosa is more common clinically, mostly caused by rhinitis, nose picking and other reasons. The general application of saline cleaning, followed by the application of recombinant human epidermal growth factor gel can promote the healing of the erosion of the mucosa. In addition, active treatment of the primary disease is the key. If the nasal mucosal erosion occurs repeatedly over a large area, it needs to be taken seriously. Prolonged nasal mucous membrane erosion is easy to cause nasal bleeding, need to be alert to nasal malignant tumors or special diseases, such as nasal cancer, congenital capillary dilatation disease. If the nasal septum mucous membrane erosion bleeding persists unrelieved, it is recommended to go to the hospital in time to do a systematic examination, and if necessary, consider taking pathology to clarify the diagnosis, and follow the doctor’s instructions to standardize the treatment.