One fetal arrest and one empty sac, to do chromosome, hysteroscopy, endocrine, autoimmune and coagulation function and male semen examination. 1. Chromosome examination: it can clarify whether the couple suffers from congenital diseases, hereditary diseases or has a family history of hereditary diseases. Couples with chromosome abnormality have to undergo genetic counseling before pregnancy to confirm whether pregnancy is possible. 2. Hysteroscopy: Hysteroscopy can find out whether there are adhesions in the uterine cavity, endometrial polyps, submucosal fibroids and so on. 3. Endocrine examination: such as progesterone, estradiol, follicle stimulating hormone, luteinizing hormone, thyroid function, etc., to understand the endocrine function. 4. Autoimmunity: such as anticardiolipin antibody, lupus anticoagulant, antinuclear antibody, rheumatoid factor, etc. 5. Coagulation function: such as D-dimer, thromboelastography, platelet aggregation rate, thrombomodulin, protein S, etc. 6. Male semen: including sperm morphology, quantity, mobility, and whether there are chromosomal abnormalities. When one fetal arrest and one empty sac occurs the cause needs to be identified under the guidance of the doctor and actively dealt with.