The main nemesis of diabetes includes the following aspects. First, the patient’s strict diabetic diet as well as exercise is the basic measure of diabetes treatment. Diabetes diet control and exercise are fundamental to the entire diabetes treatment process, and all glucose-lowering drugs are futile if not well controlled. The second aspect of diabetes is that there are a variety of glucose-lowering drugs, including oral hypoglycemic drugs, insulin and other drugs, which can help patients to take good control of blood sugar, so the glucose-lowering drugs are called the nemesis of diabetes. In fact, all methods of lowering sugar require self-restraint of the patients themselves, mainly the treatment of diet.