The first thing to understand is that prolactin is not elevated for normal women in the normal range. Prolactin is a stress hormone and any stimulus will cause it to rise. If prolactin is elevated due to stress, it does not usually affect ovulation. Because it is only present for a brief moment, the effect of prolactin on the gonadal axis is very small and negligible. However, if there is a pathological problem, prolactin is present for a long time. When prolactin is elevated, it suppresses the gonadal axis and inhibits the secretion of sex hormones, which leads to abnormal ovulation, and even suppresses estrogen and progesterone to very low levels, at which point the woman may develop pathology due to lack of estrogen, so it is important to explain the effect of prolactin on menstruation by situation. If the state is pathological, such as a long tumor in the pituitary gland or hypothyroidism, long-term use of drugs such as psychiatric patients who take antipsychotic drugs for a long time and cannot stop them at will, the psychosis will worsen after stopping them. In this case, the long-term presence of prolactin can have a strong inhibitory effect on the gonadal axis, which can lead to abnormal ovulation, infertility, irregular menstruation, and even the manifestation of hypoestrogenemia.