Pain in the middle of the buttocks is generally associated with proliferation and degeneration of the tailbone, as well as inflammation of the muscles around the tailbone and its ligaments caused by chronic strain, trauma, and congenital tailbone deformity, which is often referred to as caudalgia in the clinic, which is commonly seen in middle-aged women. If the tail pain is so severe that it affects the patient’s ability to sit or stand, topical non-steroidal anti-inflammatory drugs, such as Fitalin ointment, may be considered. If topical medications do not improve the condition, oral nonsteroidal medications, such as ibuprofen and aminophenol dihydrocodeine tablets, may be considered to improve the sterile inflammation. If oral topical drugs still can’t get the improvement, then you can consider the closed treatment, the closed drug most often choose trimethoprim and lidocaine 1:1 combination, for closed treatment.