Pleural metastasis of cancer belongs to advanced cancer, i.e. stage IV cancer, and the survival period of stage IV cancer is generally shorter, with 5-year survival rate at 10%-20%. Of course, it depends on the type of cancer, for example, pleural metastasis of lung cancer is very common, for pleural metastasis of lung cancer, corresponding treatments should be given to the metastatic foci and primary foci of lung, such as pleural metastasis causing large amount of effusion leading to respiratory difficulties, after the pleural effusion is drained sufficiently, the patient can be infused with local chemotherapeutic drugs, and at the same time, systemic treatments for lung cancer, such as chemotherapy, radiotherapy, or targeted therapy can be carried out. Through such treatment, the 5-year survival rate may be improved, but of course, it depends on the specific type of pathology, if the gene mutation positive non-small cell lung cancer, it can be combined with the use of targeted drugs and so on.