The reason for angina attack is that the oxygen supply can not meet the metabolic needs of the body, to relieve angina should reduce myocardial oxygen consumption, increase myocardial oxygen supply, to relieve the contradiction between the two supply and demand, involving three main drugs: first, nitrate drugs, mainly drugs with rapid onset and short duration of action, such as nitroglycerin, isosorbide nitrate, mainly to dilate the coronary arteries, increase the blood supply and oxygen supply to the myocardium. Second, β receptor antagonists, the representative drugs are metoprolol and bisoprolol, which can slow down the heart rate, reduce myocardial oxygen consumption, while increasing myocardial blood supply. Third, calcium antagonists, the representative drug is diltiazem, can effectively reduce the symptoms of angina, especially for patients with coronary artery spasm angina, there is no contraindication for patients with more persistent angina, the combined application of the three drugs is more ideal.