Betalucil is metoprolol tartrate, the difference between bisoprolol and this drug is mainly in pharmacokinetics, such as drug half-life, drug metabolism and so on.
Bisoprolol and metoprolol tartrate are both β1 receptor blockers, which mainly act on bronchial tubes and smooth muscle, and can play a role in bronchodilating, slowing down the heart rate, and decreasing cardiac oxygen consumption. At increasing drug doses, bisoprolol still has a beta1 receptor selective effect, while the beta1 receptor selectivity of metoprolol tartrate decreases.
Bisoprolol has a drug half-life of about 10 to 12 hours, and metoprolol tartrate has a drug half-life of about 3 to 5 hours; therefore, bisoprolol is a long-acting preparation and metoprolol tartrate is a short-acting preparation.
Bisoprolol can be excreted by both hepatic and renal routes, and metoprolol tartrate is mainly metabolized in the liver. Bisoprolol is almost completely absorbed in the gastrointestinal tract with a bioavailability of up to 90%, while metoprolol tartrate has a bioavailability of 40% to 50%.
The adverse effects and contraindications of metoprolol tartrate and bisoprolol are similar, and common adverse effects include fatigue, headache, dizziness, and bradycardia, etc. The drug is contraindicated in those who are allergic to the drug, those who have bradycardia, and those with sick sinus syndrome.
These are some of the differences between the two drugs, the specific use of drugs, need to be guided by a professional doctor.