Duodenal bulbitis pain is mainly near the upper abdomen and is usually vague or accompanied by swelling and burning sensation. Duodenal bulb refers to the upper part of the duodenum and the pylorus connected to a section of intestinal tubes, duodenal bulbitis is the duodenal bulb erosive inflammation, the main symptoms are epigastric pain, manifested as periodic, regular epigastric distension, pain in the empty stomach is obvious, pain can be relieved after eating, accompanied by acid reflux, nausea and other symptoms. The disease is associated with a variety of factors such as poor lifestyle habits, Helicobacter pylori infection, and drug damage. It can be treated for the cause of the disease. If stomach acid is obvious, omeprazole and rabeprazole can be used to inhibit the secretion of stomach acid. Eradication of Helicobacter pylori can be treated with a combination of amoxicillin, metronidazole and other drugs. Daily dietary attention to avoid spicy and stimulating food, quit smoking and drinking, do not overeat, three regular meals. Diseases should be timely medical treatment, so as not to delay the condition.