Blistering is medically referred to as blistering. Blistering of the skin after photorejuvenation may be caused by too much energy during the operation. Photorejuvenation is the use of intense pulsed light, penetrating into the deep layers of the skin, stimulating the proliferation of subcutaneous collagen, so that the dermal layer of collagen fibers and elastic fibers to change, as a way to restore the original elasticity of the skin, in the process of operation, if the irradiation of photon energy is too large, the skin blistering condition will occur. Photorejuvenation each operation about half an hour or so, after the operation is recommended to use ice cold face, if the blistering is more serious, you can take oral erythromycin capsule or external application of erythromycin ointment, daily sunscreen, to avoid hyperpigmentation. Skin blistering after photorejuvenation is an adverse reaction to the operation, it is recommended to seek medical treatment in time to avoid blistering caused by hyperpigmentation. All of the above drugs should be used in accordance with the doctor’s instructions, do not self-medication.