Erythromycin ointment can not lighten melanin. Erythromycin ointment belongs to the class of macrolide antibiotics, which is suitable for suppurative skin diseases such as impetigo, small burns, infections of ulcerated surfaces, etc., with antibacterial and antimicrobial effects. Erythromycin ointment does not have the effect of lightening melanin, if you want to lighten melanin, you can be treated by photorejuvenation, intense pulse light and other methods. Erythromycin ointment is contraindicated for those who are allergic to erythromycin, and irritation and allergic reactions are occasionally seen during the use of this drug. Avoid contact with eyes and other mucous membranes when using the drug, and stop using the drug if there is a burning sensation and itching at the site of application. If you want to lighten the melanin, it is recommended that patients go to the hospital, choose the appropriate method to lighten the melanin, and strictly prohibit the unauthorized use of drugs.