Bone tingling may be caused by several pathologies: first, it may be caused by a bone related injury. For example, if there is a contusion or fracture in the bone, the impact of the trauma itself and the sterile inflammation caused by the trauma may lead to a very obvious tingling pain; second, it may be caused by cold. For example, if the patient has a cold limb for a long time, or even frostbite, it may cause a strong inflammatory reaction around the bone, which may lead to a tingling sensation; thirdly, it may be caused by bone related infection. For example, if a patient has septic osteomyelitis or tuberculosis, the inflammation or destruction of bone may be caused by the above infection, which may lead to a tingling sensation in the bone; fourth, it may also be caused by some occupational diseases in the bone. For example, when a bone tumor is present, there may be similar symptoms.