Today an outpatient, male, 45 years old, with a history of hypertension for 2 years, has been taking oral enalapril maleate tablets with fair blood pressure control. However, 1 week ago after a physical examination at a medical examination facility, the doctor suggested adding folic acid tablets. The patient read the instructions of the folic acid tablets and was puzzled. She suspected that the doctor had prescribed the wrong medicine. This is because folic acid tablets are a medicine for anemia, which she does not have. In response to the patient’s puzzlement, the patient was first calmed down and took out the laboratory test sheet and looked at it carefully. The test indicated that the blood lipids, blood sugar, liver and kidney functions were normal. However, there is one indicator that is higher than normal, and this indicator is called homocysteine, abbreviated as Hcy. Homocysteine is an independent risk factor for hypertension, cerebral infarction, heart disease, etc. For every 5umol/L unit increase, the risk of cardiovascular disease and peripheral atherosclerosis increases by 60-80%. Good control of homocysteine greatly reduces the incidence of hypertension, heart disease, and cerebral infarction. Therefore, homocysteine has been included as a routine screening test in most medical check-ups. So what can be done to treat hyperhomocysteinemia? One can improve the structure of the diet with appropriate supplements of nuts, fruits, and fresh vegetables, in addition to weight control and more exercise. In addition, oral folic acid tablets and vitamin B1 can be taken to lower homocysteine. It was through the explanation that it dawned on the patient. Patients with hypertension, have you had your homocysteine checked?