An iodine 131 uptake rate test can be done to differentiate between hyperthyroidism (except iodine hyperthyroidism) and non-hyperthyroid thyrotoxicosis (hyperthyroidism is short for hyperthyroidism). Patients with Graves’ disease have elevated iodine 131 uptake rates, more often than not with an anterior shift of the peak. Patients with multinodular toxic goiter and autonomous high-functioning adenomas of the thyroid gland have elevated or normal iodine 131 uptake rates. Patients with iodine hyperthyroidism and non-hyperthyrotoxic thyrotoxicosis have normal or decreased iodine 131 uptake rates. It is recommended that patients who need to do iodine 131 uptake rate examination should go to regular hospitals in time to complete the relevant examinations and standardize the diagnosis and treatment under the guidance of the doctor, so as to avoid delaying the condition and causing serious consequences.