Dapoxetine eat down how long it takes to see the effect is different from person to person, Dapoxetine will be rapidly absorbed after oral intake, about 1 to 2 hours to reach the peak plasma concentration of the drug, so clinically most patients see the effect of the drug about 1 hour after use. Dapoxetine is a selective 5-hydroxytryptamine inhibitor, mainly used for the treatment of men aged 18 to 64 years of age with premature ejaculation, including: persistent or recurrent ejaculation due to minimal sexual stimulation of the penis prior to, during, or shortly after insertion into the vagina, and prior to sexual satisfaction; significant personal distress or interpersonal difficulties due to premature ejaculation; and poor ejaculatory control. Adverse reactions to dapoxetine are mainly mild dizziness and nausea, but are generally transient and disappear quickly. In addition, dapoxetine is contraindicated in persons known to have had an allergic reaction to it, in patients with moderate or severe hepatic impairment and significant cardiac pathology, in patients on strong cytochrome P4503A4 inhibitors, in women, avoiding alcohol, and in patients with a history of mania, hypomania, or bipolar disorder. Dapoxetine should not be used in combination with monoamine oxidase inhibitors or thioridazine, not within 14 days of discontinuing monoamine oxidase inhibitors or thioridazine, and not within 7 days of discontinuing dapoxetine. If you need to use Dapoxetine, please consult with a medical professional and use the medication as prescribed.