There are many clinical manifestations of renal tubular disease, as follows: 1) polyuria, weakness, poor nasal function and nausea, which may be caused by acidosis; 2) small amount of proteinuria, which may be caused by the decrease of renal tubular protein reabsorption capacity; 3) urinary sugar, which may be caused by the decrease of renal reabsorption capacity of sugar; 4) low potassium and high potassium symptoms, which may be caused by weakness and poor nasal function in patients with low potassium and arrhythmia in patients with high potassium. In conclusion, there are many clinical manifestations of glomerular diseases, so it is recommended that patients should seek medical consultation and early treatment when they have uncomfortable symptoms.