Urolithiasis and gallstones have pain, more factors of stone formation, metabolic abnormalities, and infectious causes in common. 1. Pain: For urolithiasis, stones are mostly found in the urinary tract and bladder, which can be felt as a dull ache in daily life or pain during urination. For gallstones, the stones are present in the gallbladder, and the strong contraction of the gallbladder leads to biliary colic. 2. Stone formation factors are more: urolithiasis and gallstone stone formation factors are comprehensive, daily diet, bad habits may all together lead to cholesterol raise the formation of gallstones, long-term bedridden can also lead to urolithiasis. 3. Abnormal metabolism: Urolithiasis stones may be caused by metabolic disorders such as hyperparathyroidism and hyperuricemia. The most common type of gallstones is cholesterol stones. Cholesterol cannot be metabolized properly and accumulates in the gallbladder or bile ducts to form stones. 4. Infectious causes: Urethritis is formed when bacteria break down urea in the urine through a series of transformations to form deposits, products of bacterial infection, necrotic tissue and other substances. Gallstones may be caused by bacterial infection of the gallbladder. The causes of urolithiasis and gallstones are complex and numerous, so if you feel unwell, you should seek medical attention in a timely manner, under the professional guidance of your doctor, and follow the doctor’s instructions to cooperate with the treatment.